{"type":"standard","title":"Dicer","displaytitle":"Dicer","namespace":{"id":0,"text":""},"wikibase_item":"Q21111297","titles":{"canonical":"Dicer","normalized":"Dicer","display":"Dicer"},"pageid":593203,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/1/1e/Mouse_dicer.jpg/330px-Mouse_dicer.jpg","width":320,"height":320},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/1/1e/Mouse_dicer.jpg","width":500,"height":500},"lang":"en","dir":"ltr","revision":"1248126973","tid":"1c0678fd-7d0d-11ef-99cb-d0256aba1556","timestamp":"2024-09-27T20:14:33Z","description":"Enzyme that cleaves double-stranded RNA (dsRNA) into short dsRNA fragments","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Dicer","revisions":"https://en.wikipedia.org/wiki/Dicer?action=history","edit":"https://en.wikipedia.org/wiki/Dicer?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Dicer"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Dicer","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Dicer","edit":"https://en.m.wikipedia.org/wiki/Dicer?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Dicer"}},"extract":"Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the RNase III family, Dicer cleaves double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short double-stranded RNA fragments called small interfering RNA and microRNA, respectively. These fragments are approximately 20–25 base pairs long with a two-base overhang on the 3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic component Argonaute, which is an endonuclease capable of degrading messenger RNA (mRNA).","extract_html":"
Dicer, also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. Being part of the RNase III family, Dicer cleaves double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short double-stranded RNA fragments called small interfering RNA and microRNA, respectively. These fragments are approximately 20–25 base pairs long with a two-base overhang on the 3′-end. Dicer facilitates the activation of the RNA-induced silencing complex (RISC), which is essential for RNA interference. RISC has a catalytic component Argonaute, which is an endonuclease capable of degrading messenger RNA (mRNA).
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{"type":"standard","title":"Sirpur (T)","displaytitle":"Sirpur (T)","namespace":{"id":0,"text":""},"wikibase_item":"Q7530597","titles":{"canonical":"Sirpur_(T)","normalized":"Sirpur (T)","display":"Sirpur (T)"},"pageid":11014759,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/7/79/Sirpur_fort.jpg/330px-Sirpur_fort.jpg","width":320,"height":172},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/7/79/Sirpur_fort.jpg","width":1100,"height":592},"lang":"en","dir":"ltr","revision":"1276752451","tid":"83ae9258-ef9b-11ef-876f-31a880805761","timestamp":"2025-02-20T15:01:08Z","description":"Town in Telangana, India","description_source":"local","coordinates":{"lat":19.4833,"lon":79.6},"content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Sirpur_(T)","revisions":"https://en.wikipedia.org/wiki/Sirpur_(T)?action=history","edit":"https://en.wikipedia.org/wiki/Sirpur_(T)?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Sirpur_(T)"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Sirpur_(T)","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Sirpur_(T)","edit":"https://en.m.wikipedia.org/wiki/Sirpur_(T)?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Sirpur_(T)"}},"extract":"Sirpur (T) is a town and a mandal in Komaram Bheem district of the Indian state of Telangana.","extract_html":"
Sirpur (T) is a town and a mandal in Komaram Bheem district of the Indian state of Telangana.
"}{"fact":"Cats purr at the same frequency as an idling diesel engine, about 26 cycles per second.","length":87}
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